Systems and methods for providing a door seal system for top-hanging sliding doors. In some implementations, two angled mating surfaces are used, one angled surface on a fixed frame and one reversed angled surface on the slideable door panel. The slideable door panel slides directly parallel to the fixed door frame. A mating seal surface is created that is only in frictional contact for a small portion of the linear slide distance of the door panel. In some implementations, rather than placing two opposing angled seal surfaces, the sealing system has one angled surface on the fixed door frame. In such implementations, the sliding door panel is adjusted to be in a reverse angled orientation relative to the angled surface of the fixed door frame. Seal designs for the rear vertical edge of the slideable door panel are also provided herein.