Compensation for threshold voltage mismatches in cross-coupled pairs of transistors and related systems, devices, and methods are disclosed. An apparatus includes a cross-coupled pair of transistors, and a compensation pair of transistors. The cross-coupled pair of transistors includes a first transistor and a second transistor. A first gate of the first transistor is coupled to a first bit line and a second gate of the second transistor coupled to a second bit line. The compensation pair of transistors includes a third transistor and a fourth transistor. The third transistor is coupled in series with the first transistor between a first source of the first transistor and a common source line. The fourth transistor is coupled in series with the second transistor between a second source of the second transistor and the common source line. A memory device includes the sense amplifier. A computing system includes the memory device.