Invention Grant
- Patent Title: Prevention and treatment of diabetic nephropathy
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Application No.: US16338834Application Date: 2017-10-03
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Publication No.: US11291641B2Publication Date: 2022-04-05
- Inventor: Paolo Fiorina , Roberto Bassi , Andrea Vergani , Marcello Allegretti
- Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION , DOMPE FARMACEUTICI S.P.A.
- Applicant Address: US MA Boston; IT Milan
- Assignee: THE CHILDREN'S MEDICAL CENTER CORPORATION,DOMPE FARMACEUTICI S.P.A.
- Current Assignee: THE CHILDREN'S MEDICAL CENTER CORPORATION,DOMPE FARMACEUTICI S.P.A.
- Current Assignee Address: US MA Boston; IT Milan
- Agency: Nixon Peabody LLP
- Agent David S. Resnick; Jeanne Jodoin
- International Application: PCT/US2017/054916 WO 20171003
- International Announcement: WO2018/067548 WO 20180412
- Main IPC: A61K31/18
- IPC: A61K31/18 ; A61K31/426 ; A61P3/10 ; A61P13/12 ; A61K45/06 ; G01N33/68
Abstract:
Embodiments herein disclose methods relating to diabetic nephropathy (DN); methods for preventing the onset and also for preventing the progressing of DN, as well as the treatment of DN in diabetic subjects comprising administering reparixin and/or ladarixin which are inhibitors of CXCL8 receptor CXCR1 and CXCR2 activation.
Public/Granted literature
- US20190224148A1 PREVENTION AND TREATMENT OF DIABETIC NEPHROPATHY Public/Granted day:2019-07-25
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