Invention Grant
- Patent Title: Methods and compositions for modulating Akt3
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Application No.: US16989481Application Date: 2020-08-10
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Publication No.: US11291719B2Publication Date: 2022-04-05
- Inventor: Samir N. Khleif , Mikayel Mkrtichyan , Iryna Lebedyeva , Thomas Albers
- Applicant: Augusta University Research Institute, Inc.
- Applicant Address: US GA Augusta
- Assignee: Augusta University Research Institute, Inc.
- Current Assignee: Augusta University Research Institute, Inc.
- Current Assignee Address: US GA Augusta
- Agency: Smith, Gambrell & Russell
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K39/39 ; C07D401/14 ; A61P35/00 ; A61K39/00
Abstract:
Compounds and compositions for selectively modulating Akt3 are provided. Methods of using the compounds are also provided. Because Akt3 modulates the suppressive function of natural Tregs and the polarization of induced Tregs, the disclosed compounds are useful for modulating immune responses.
Information query
