Invention Grant
- Patent Title: Anhydrous sodium thiosulfate and formulations thereof
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Application No.: US17005997Application Date: 2020-08-28
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Publication No.: US11291728B2Publication Date: 2022-04-05
- Inventor: Thomas Claiborne Lovelace , Joseph Alexander Moore, III , Christopher McKinnon Lee , Daniel Logan Kirschner
- Applicant: Fennec Pharmaceuticals, Inc.
- Applicant Address: US NC Research Triangle Park
- Assignee: Fennec Pharmaceuticals, Inc.
- Current Assignee: Fennec Pharmaceuticals, Inc.
- Current Assignee Address: US NC Research Triangle Park
- Agency: Knowles Intellectual Property Strategies, LLC
- Main IPC: A61K47/20
- IPC: A61K47/20 ; A61K33/243 ; A61K9/00 ; A61K9/08 ; A61K33/04 ; A61K47/02 ; A61K47/18
Abstract:
Described herein is anhydrous sodium thiosulfate, methods for synthesizing anhydrous sodium thiosulfate, pharmaceutical compositions thereof, and methods of treating ototoxicity. Anhydrous sodium thiosulfate is synthesized from sodium sulfite, sulfur, and cetylpyridinium chloride. The anhydrous sodium thiosulfate is formulated into a pharmaceutical composition comprising a buffer and solvent. These compositions are useful for eliminating or reducing ototoxicity in pediatric patients receiving platinum based chemotherapeutics.
Public/Granted literature
- US20210015923A1 ANHYDROUS SODIUM THIOSULFATE AND FORMULATIONS THEREOF Public/Granted day:2021-01-21
Information query
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