Invention Grant
- Patent Title: Calpain modulators and therapeutic uses thereof
-
Application No.: US16312916Application Date: 2017-06-29
-
Publication No.: US11292801B2Publication Date: 2022-04-05
- Inventor: Brad Owen Buckman , Shendong Yuan , John Beamond Nicholas , Jingyuan Ma , Kumaraswamy Emayan , Marc Adler
- Applicant: Blade Therapeutics, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Blade Therapeutics, Inc.
- Current Assignee: Blade Therapeutics, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Knobbe Martens Olson & Bear LLP
- International Application: PCT/US2017/040109 WO 20170629
- International Announcement: WO2018/009417 WO 20180111
- Main IPC: C07D498/18
- IPC: C07D498/18 ; A61P1/16 ; A61P13/12 ; A61P11/00 ; C07D245/06 ; C07D267/00 ; C07D405/12 ; C07D407/12 ; C07D413/12 ; C07D471/18 ; C07D498/04
Abstract:
Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to macrocyclic α-keto amide derivatives and their use as therapeutic agents.
Information query
