Invention Grant
- Patent Title: Long-acting prodrugs of entecavir, preparing methods and uses thereof
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Application No.: US16650920Application Date: 2018-09-29
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Publication No.: US11292811B2Publication Date: 2022-04-05
- Inventor: Jiancun Zhang , Deyao Li , Yiqian Zhou , Yiwu Wu , Yan Liu
- Applicant: GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD
- Applicant Address: CN Guangzhou
- Assignee: GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD
- Current Assignee: GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD
- Current Assignee Address: CN Guangzhou
- Agency: Schmeiser, Olsen & Watts, LLP
- Priority: CN201710903592.1 20170929
- International Application: PCT/CN2018/108663 WO 20180929
- International Announcement: WO2019/062924 WO 20190404
- Main IPC: C07H19/16
- IPC: C07H19/16 ; A61K9/00
Abstract:
Provided are a long-acting prodrug of Entecavir, preparation method and use thereof, wherein the prodrug of Entecavir has a structure of formula I. The prodrug of Entecavir can be released slowly, sustainably and steady, and converted to active compound of Entecavir to achieve a long-acting effect.
Public/Granted literature
- US20200239513A1 LONG-ACTING PRODRUGS OF ENTECAVIR, PREPARING METHODS AND USES THEREOF Public/Granted day:2020-07-30
Information query
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