Invention Grant
- Patent Title: Type I and type III interferon fusion molecules and methods for use thereof
-
Application No.: US16604666Application Date: 2018-05-01
-
Publication No.: US11292823B2Publication Date: 2022-04-05
- Inventor: Sergei V. Kotenko , Joan Durbin , Viralkumar Rameshkumar Davra
- Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
- Applicant Address: US NJ New Brunswick
- Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
- Current Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
- Current Assignee Address: US NJ New Brunswick
- Agency: Licata & Tyrrell P.C.
- International Application: PCT/US2018/030370 WO 20180501
- International Announcement: WO2018/204312 WO 20181108
- Main IPC: C07K14/56
- IPC: C07K14/56 ; C07K14/565 ; A61K38/00 ; A01N37/18 ; C07K14/57
Abstract:
Fusion molecules composed of a type I interferon protein or portion thereof and a type III interferon protein or portion thereof, pharmaceutical compositions containing the fusion molecules, and methods for their use in inhibiting infection, inhibiting or treating cancer, inducing signaling of transcription of IFN-stimulated genes through an IFN-αR2 chain in a subject suffering from an infection which degrades or downregulates an IFN-αR1 chain, and treating various diseases or conditions are provided.
Public/Granted literature
- US20200071375A1 TYPE I AND TYPE III INTERFERON FUSION MOLECULES AND METHODS FOR USE THEREOF Public/Granted day:2020-03-05
Information query
