Invention Grant
- Patent Title: Pharmaceutical preparation comprising recombinant hCG
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Application No.: US16709810Application Date: 2019-12-10
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Publication No.: US11292824B2Publication Date: 2022-04-05
- Inventor: Ian Cottingham , Daniel Plaksin , Richard White
- Applicant: Ferring B.V.
- Applicant Address: NL Hoofddorp
- Assignee: Ferring B.V.
- Current Assignee: Ferring B.V.
- Current Assignee Address: NL Hoofddorp
- Agency: Foley & Lardner LLP
- Priority: EP09252360 20091005
- Main IPC: C07K14/575
- IPC: C07K14/575 ; C07K14/59 ; C12P21/00 ; A61K38/16

Abstract:
Described are pharmaceutical compositions comprising recombinant human chorionic gonadotropin (hCG) and follicle stimulating hormone (FSH), wherein the recombinant hCG in the composition comprises α2,3- and α2,6-sialylation and comprises mono-(1S), di-(2S), tri-(3S) and tetra-(4S) sialylated glycan structures. The recombinant hCG may be obtained by expression in a human cell line, such as the PER.C6 cell line, optionally wherein the cell line is modified using α2,3-sialyltransferase.
Public/Granted literature
- US20200247863A1 PHARMACEUTICAL PREPARATION COMPRISING RECOMBINANT HCG Public/Granted day:2020-08-06
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