Disclosed embodiments relate to systems and methods for performing duplicate detection instructions on two-dimensional (2D) data. In one example, a processor includes fetch circuitry to fetch an instruction, decode circuitry to decode the fetched instruction having fields to specify an opcode and locations of a source matrix comprising M×N elements and a destination, the opcode to indicate execution circuitry is to use a plurality of comparators to discover duplicates in the source matrix, and store indications of locations of discovered duplicates in the destination. The execution circuitry to execute the decoded instruction as per the opcode.