Invention Grant
- Patent Title: Methods of use and pharmaceutical combinations of HDAC inhibitors with BET inhibitors
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Application No.: US16305567Application Date: 2017-06-09
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Publication No.: US11298354B2Publication Date: 2022-04-12
- Inventor: Kwok-kin Wong , Yan Liu , Dennis O. Adeegbe , Steven Norman Quayle
- Applicant: DANA-FARBER CANCER INSTITUTE, INC. , ACETYLON PHARMACEUTICALS, INC.
- Applicant Address: US MA Boston; US MA Boston
- Assignee: DANA-FARBER CANCER INSTITUTE, INC.,ACETYLON PHARMACEUTICALS, INC.
- Current Assignee: DANA-FARBER CANCER INSTITUTE, INC.,ACETYLON PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Boston; US MA Boston
- Agency: Lathrop GPM LLP
- Agent Brian C. Trinque
- International Application: PCT/US2017/036847 WO 20170609
- International Announcement: WO2017/214565 WO 20171214
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61P35/00 ; A61K31/437 ; A61K31/551
Abstract:
The disclosure relates to pharmaceutical combinations comprising an HDAC6 selective inhibitor and a BET inhibitor for the treatment of cancer in a subject in need thereof. Also provided herein are methods for treating cancer in a subject in need thereof, comprising administering to the subject an effective amount of an HDAC6 selective inhibitor and a BET inhibitor.
Public/Granted literature
- US20200323848A1 METHODS OF USE AND PHARMACEUTICAL COMBINATIONS OF HDAC INHIBITORS WITH BET INHIBITORS Public/Granted day:2020-10-15
Information query
