A vacuum preservation machine capable of printing date codes includes an upper cover and a lower cover connected together and capable of opening and closing, the upper cover and the lower cover are respectively provided with an upper sealing foam and a lower sealing foam at corresponding positions, an upper side of the lower cover is provided with a preservation bag and the opening of the preservation bag is located on the inner side of the lower sealing foam, when the upper cover is closed, the upper sealing foam and lower sealing foam can be fit together to formed a sealing chamber to vacuum the preservation bag, the upper cover is provided with a printing wheel at the position of the inner side of the upper sealing foam; the lower cover is provided with a block at the position of the inner side of the lower sealing foam.