Invention Grant
- Patent Title: Synthesis of key intermediate of KRAS G12C inhibitor compound
-
Application No.: US16685841Application Date: 2019-11-15
-
Publication No.: US11299491B2Publication Date: 2022-04-12
- Inventor: Andrew Thomas Parsons , Brian McNeil Cochran , William Powazinik, IV , Marc Anthony Caporini
- Applicant: Amgen Inc.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Markus Bergauer
- Main IPC: C07C63/33
- IPC: C07C63/33 ; C07C69/76 ; C07D471/04 ; C07D471/14 ; C07C309/24
Abstract:
The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure useful for the synthesis of compounds that target KRAS G12C mutations, such as
Public/Granted literature
- US20200216446A1 SYNTHESIS OF KEY INTERMEDIATE OF KRAS G12C INHIBITOR COMPOUND Public/Granted day:2020-07-09
Information query
