Invention Grant
- Patent Title: Spiro-lactam NMDA receptor modulators and uses thereof
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Application No.: US16321905Application Date: 2017-08-01
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Publication No.: US11299495B2Publication Date: 2022-04-12
- Inventor: M. Amin Khan
- Applicant: Aptinyx Inc.
- Applicant Address: US IL Evanston
- Assignee: Aptinyx Inc.
- Current Assignee: Aptinyx Inc.
- Current Assignee Address: US IL Evanston
- Agency: Goodwin Procter LLP
- International Application: PCT/US2017/044838 WO 20170801
- International Announcement: WO2018/026779 WO 20180208
- Main IPC: C07D487/10
- IPC: C07D487/10 ; C07D471/10 ; A61P25/28 ; A61P25/02 ; A61P25/22 ; A61P25/18 ; A61P25/14 ; A61P25/24

Abstract:
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders. Orally delivered formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
Public/Granted literature
- US20190177334A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF Public/Granted day:2019-06-13
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