Invention Grant
- Patent Title: Compositions comprising a chimeric bacterial surface layer protein and methods of use thereof
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Application No.: US16651160Application Date: 2018-09-25
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Publication No.: US11299520B2Publication Date: 2022-04-12
- Inventor: Gayatri Vedantam , Virinchipuram Viswanathan
- Applicant: Arizona Board of Regents on Behalf of the University of Arizona
- Applicant Address: US AZ Tucson
- Assignee: Arizona Board of Regents on Behalf of the University of Arizona
- Current Assignee: Arizona Board of Regents on Behalf of the University of Arizona
- Current Assignee Address: US AZ Tucson
- Agency: Casimir Jones, S.C.
- Agent J. Mitchell Jones
- International Application: PCT/US2018/052656 WO 20180925
- International Announcement: WO2019/067447 WO 20190404
- Main IPC: A61K35/74
- IPC: A61K35/74 ; C07K14/33 ; C07K14/335 ; C12N9/90 ; C12N15/62 ; A61K9/00 ; A61K38/00
Abstract:
The invention features engineered probiotic lacto acid bacteria (LAB) expressing a chimeric Clostridium difficile/Lactobacillus acidophilus SlpA, or fragment thereof, and its use for the treatment or prevention of Clostridium difficile infection and gut colonization.
Public/Granted literature
- US20200239527A1 COMPOSITIONS COMPRISING A CHIMERIC BACTERIAL SURFACE LAYER PROTEIN AND METHODS OF USE THEREOF Public/Granted day:2020-07-30
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