Invention Grant
- Patent Title: Modified lipase and use thereof
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Application No.: US16639871Application Date: 2018-08-17
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Publication No.: US11299722B2Publication Date: 2022-04-12
- Inventor: Kazunori Yoshida , Tetsuya Takahashi , Kazuhiko Ishikawa
- Applicant: AMANO ENZYME INC.
- Applicant Address: JP Nagoya
- Assignee: AMANO ENZYME INC.
- Current Assignee: AMANO ENZYME INC.
- Current Assignee Address: JP Nagoya
- Agency: Locke Lord LLP
- Priority: JPJP2017-168995 20170901
- International Application: PCT/JP2018/030463 WO 20180817
- International Announcement: WO2019/044531 WO 20190307
- Main IPC: C12N9/20
- IPC: C12N9/20 ; C12P7/64
Abstract:
The present invention has an object of providing a modified lipase having excellent stability and reactivity at a high temperature. Provided is a modified lipase with improved reactivity and/or stability at a high temperature, the modified lipase having an amino acid sequence including one or more amino acid substitutions which are selected from the group consisting of T130C-S153C, A249P, F259Y, S282P, S283Y and S300P in the amino acid sequence represented by SEQ ID NO: 1, or an amino acid sequence having 90% or more sequence identity therewith.
Information query
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