The present disclosure discloses a laboratory test device for permeation grouting of impermeable material, which comprises a slurry storage device with a stirrer, a grouting pump, electromagnetic flow meters, pressure sensors, a pressure chamber, a slurry collection tank, a pH value meter, a conductivity meter, electronic scales, an image acquisition system and a computer system. The computer system automatically acquires related data to save the labor, and the data is recorded completely so as to facilitate tests and researches. Software installed in the computer system can automatically process the data and displays a permeability coefficient in real time so as to achieve quick determination and real-time display of the permeability coefficient and facilitate development of laboratory tests and researches. Three pressure sensors are arranged on an organic glass cylinder of the pressure chamber at the equal intervals.