Invention Grant
- Patent Title: Esters of dihydrotetrabenazine
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Application No.: US16762747Application Date: 2018-11-07
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Publication No.: US11306082B2Publication Date: 2022-04-19
- Inventor: Yuhua Li , Chen-Chang Lee , Wen-Yen Huang
- Applicant: Foresee Pharmaceuticals Co., Ltd.
- Applicant Address: TW Taipei
- Assignee: Foresee Pharmaceuticals Co., Ltd.
- Current Assignee: Foresee Pharmaceuticals Co., Ltd.
- Current Assignee Address: TW Taipei
- Agency: MagStone Law, LLP
- Agent Enshan Hong
- International Application: PCT/US2018/059657 WO 20181107
- International Announcement: WO2019/094491 WO 20190516
- Main IPC: C07D455/06
- IPC: C07D455/06 ; A61K47/44

Abstract:
The present invention relates to a compound of formula (I) including any stereochemically isomeric form thereof, or a pharmaceutically acceptable salt thereof. wherein R1 is —C(═O)O-alkyl, carbonate ester, or —C(═O)-alkyl, ester, or —C(═O)N-alkyl, carbamate ester and wherein R2 is —CH3 or —CD3. The alkyl ester can contain saturated or unsaturated C12 to C26 alkyl carbon. The alkyl carbon chain can have either a straight, branched, noncyclic, cyclic, unsubstituted or substituted structure.
Public/Granted literature
- US20200270241A1 ESTERS OF DIHYDROTETRABENAZINE Public/Granted day:2020-08-27
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