Invention Grant
- Patent Title: Gamma-carboline compounds for the detection of Tau aggregates
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Application No.: US16964952Application Date: 2019-01-22
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Publication No.: US11306089B2Publication Date: 2022-04-19
- Inventor: Mathias Berndt , Andre Müller , Felix Oden , Hanno Schieferstein , Heribert Schmitt-Willich , Heiko Kroth , Jérôme Molette
- Applicant: AC IMMUNE SA , LIFE MOLECULAR IMAGING SA
- Applicant Address: CH Lausanne; CH Matran
- Assignee: AC IMMUNE SA,LIFE MOLECULAR IMAGING SA
- Current Assignee: AC IMMUNE SA,LIFE MOLECULAR IMAGING SA
- Current Assignee Address: CH Lausanne; CH Matran
- Agency: Millen White Zelano & Branigan, PC
- Priority: EP18153325 20180124
- International Application: PCT/EP2019/051495 WO 20190122
- International Announcement: WO2019/145291 WO 20190801
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14 ; C07D471/04 ; A61K51/04 ; C07B59/00 ; C07D513/14

Abstract:
The present invention relates to novel compounds of the formula (II) and formula (III) that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other tauopathies using Positron Emission Tomography (PET) Imaging.
Public/Granted literature
- US20210047321A1 GAMMA-CARBOLINE COMPOUNDS FOR THE DETECTION OF TAU AGGREGATES Public/Granted day:2021-02-18
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