Invention Grant
- Patent Title: Anti-NPR1 antibodies and uses thereof
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Application No.: US16657000Application Date: 2019-10-18
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Publication No.: US11306148B2Publication Date: 2022-04-19
- Inventor: Michael Dunn , Jia Su , Jason Mastaitis , Jesper Gromada , Lori Morton
- Applicant: Regeneron Pharmaceuticals, Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Merchant & Gould P.C.
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; A61P9/02 ; A61P3/04 ; A61P9/12 ; A61K9/00 ; A61K45/06
Abstract:
The present invention provides monoclonal antibodies that bind to the natriuretic peptide receptor 1 (NPR1) protein, and methods of use thereof. In various embodiments of the invention, the antibodies are fully human antibodies that bind to NPR1. In some embodiments, the antibodies of the invention are useful for activating NPR1 activity, thus providing a means of treating or preventing a disease, disorder or condition associated with NPR1 in humans.
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