Invention Grant
- Patent Title: Assessment of cellular signaling pathway activity using linear combination(s) of target gene expressions
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Application No.: US14652805Application Date: 2013-12-18
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Publication No.: US11306360B2Publication Date: 2022-04-19
- Inventor: Hendrik Jan Van Ooijen , Wilhelmus Franciscus Johannes Verhaegh , Paul Arnold Van De Wiel
- Applicant: KONINKLIJKE PHILIPS N.V.
- Applicant Address: NL Eindhoven
- Assignee: KONINKLIJKE PHILIPS N.V.
- Current Assignee: KONINKLIJKE PHILIPS N.V.
- Current Assignee Address: NL Eindhoven
- International Application: PCT/IB2013/061066 WO 20131218
- International Announcement: WO2014/102668 WO 20140703
- Main IPC: G01N33/48
- IPC: G01N33/48 ; C12Q1/6886 ; G06N5/04 ; G16B5/00 ; G16B25/00 ; G16B25/10 ; G16B40/00
Abstract:
The present application mainly relates to specific methods for inferring activity of a cellular signaling pathway in tissue and/or cells of a medical subject based at least on expression levels of one or more target gene(s) of the cellular signaling pathway measured in an extracted sample of the tissue and/or cells of the medical subject, an apparatus comprising a digital compressor configured to perform such methods and a non-transitory storage medium storing instructions that are executable by a digital processing device to perform such methods.
Public/Granted literature
- US20150347672A1 ASSESSMENT OF CELLULAR SIGNALING PATHWAY ACTIVITY USING LINEAR COMBINATION(S) OF TARGET GENE EXPRESSIONS Public/Granted day:2015-12-03
Information query
