Biological organs and tissues can be identified using imaging or other data representing the organs and tissues. Example imaging modalities include 3D x-rays (including CT scans), MRI imaging, and millimeter wavelength scanning commonly used for airport security. Biomarkers may be identified as part of daily activities, such as airport travel, applying for government identifications (licenses and passports), medical appointments, and fitness monitoring. These imaging approaches may create static and dynamic data sets for comparison against existing data sets in a database. Biomarkers may identify (and predict) normal, morphological or morbidity changes over time. Such imaging biomarkers may securely identify individuals at critical checkpoints such as airports and border crossings. This approach is also applicable to plant identification and can provide a secure chain of custody for virtually any object.