The claimed solution relates to a method of making transactions in the blockchain framework using a protected hardware and software complex to ensure secure storage of digital currencies (cryptocurrencies) and control the entire lifecycle of multiple wallets simultaneously to make transactions in the blockchain network. Basic features of the hardware and software complex include the effective control over the entire life cycle of cold wallets, generation of digital wallets and secure storage of their private keys in an isolated environment using the hardware security modules (HSM), as well as maintaining the multiple level authentication of blockchain transactions. It is possible to use all the features of the complex due to compatibility with the application programming interface (API), which enables to integrate the complex into the existing software solutions, for example, banking systems.