A nonvolatile memory device includes a substrate having an upper surface and a channel structure disposed over the substrate. The channel structure includes at least one channel layer pattern and at least one interlayer insulation layer pattern, which are alternately stacked in a first direction perpendicular to the upper surface, and the channel structure extends in a second direction perpendicular to the first direction. The nonvolatile memory device includes a resistance change layer disposed over the substrate and on at least a portion of one sidewall surface of the channel structure, a gate insulation layer disposed over the substrate and on the resistance change layer, and a plurality of gate line structures disposed over the substrate, each contacting a first surface of the gate insulation layer and disposed to be spaced apart from each other in the second direction.