Invention Grant
- Patent Title: Combination of small molecule CD-47 inhibitors with other anti-cancer agents
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Application No.: US16678594Application Date: 2019-11-08
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Publication No.: US11311517B2Publication Date: 2022-04-26
- Inventor: Muralidhara Ramachandra , Pottayil Govindan Nair Sasikumar , Girish Chandrappa Daginakatte , Kiran Aithal Balkudru
- Applicant: Aurigene Discovery Technologies Limited
- Applicant Address: IN Bangalore
- Assignee: Aurigene Discovery Technologies Limited
- Current Assignee: Aurigene Discovery Technologies Limited
- Current Assignee Address: IN Bangalore
- Agency: Duane Morris LLP
- Agent Thomas J. Kowalski; Deborah L. Lu
- Priority: IN201841042108 20181108
- Main IPC: A61K31/4245
- IPC: A61K31/4245 ; A61P35/00 ; A61K45/06 ; C07K16/28
Abstract:
The present invention relates to a composition of a CD47-SIRPα blocking agent and one or more anti-cancer agent(s), where the CD47-SIRPα blocking agents are represented by a compound of formula (I). The present invention also relates to a method of treating a cancer in a subject by administering a therapeutically effective amount of a CD47-SIRPα blocking agent represented by formula (I) in combination with one or more anti-cancer agent(s).
Public/Granted literature
- US20200147054A1 Combination of Small Molecule CD-47 Inhibitors with Other Anti-Cancer Agents Public/Granted day:2020-05-14
Information query
