- Patent Title: Satiation peptides for weight loss and altered taste sensitivity
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Application No.: US15489717Application Date: 2017-04-17
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Publication No.: US11311633B2Publication Date: 2022-04-26
- Inventor: Sergei Zolotukhin , Sean M. Crosson , Cedrick Shawn Dotson , Seth Currlin , Andres Acosta
- Applicant: University of Florida Research Foundation, Incorporated
- Applicant Address: US FL Gainesville
- Assignee: University of Florida Research Foundation, Incorporated
- Current Assignee: University of Florida Research Foundation, Incorporated
- Current Assignee Address: US FL Gainesville
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K38/22
- IPC: A61K38/22 ; A61K38/26 ; C07K14/47 ; C07K14/575 ; C07K14/605 ; A61K48/00 ; A61K9/00 ; C12N15/86

Abstract:
The present application provides methods and compositions for AAV-mediated delivery of PYY and Glucagon-like Peptide 1 or an analog thereof (e.g., Exendin-4) to a subject (e.g., the saliva of a subject). In some embodiments, compositions and methods for topical delivery of Ex-4 and PYY peptides also are provided. Methods and compositions are useful to promote weight loss and/or altered lipid taste sensitivity, as well as for the treatment of diabetes.
Public/Granted literature
- US20170326257A1 SATIATION PEPTIDES FOR WEIGHT LOSS AND ALTERED TASTE SENSITIVITY Public/Granted day:2017-11-16
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