A wire harness includes a plurality of insulated electric wires, a sheath covering a part in a longitudinal direction of the insulated wires, and a branching portion fixing member covering an end portion of the sheath with the insulated wires guided out therefrom, and one-parts in respective longitudinal directions of the insulated wires being guided out from the end portion of the sheath. The branching portion fixing member includes a plurality of guiding-out portions to guide out the one-parts of the plurality of insulated wires respectively. The wire harness is provided with a protective tube to cover at least one of the guiding-out portions, and the insulated wire guided out from the at least one of the guiding-out portions, and a tightening member to tighten and fix one end portion of the protective tube to an outer peripheral surface of the at least one of the guiding-out portions.