Invention Grant
![7H-azulene [1,2,3-i,j] isoquinolin-7-one compound, single crystal and use thereof](/docs/US/2022-04-26/US11312687B2/abs.jpg.600x600.jpg)
- Patent Title: 7H-azulene [1,2,3-i,j] isoquinolin-7-one compound, single crystal and use thereof
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Application No.: US16097776Application Date: 2018-03-22
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Publication No.: US11312687B2Publication Date: 2022-04-26
- Inventor: Shunxiang Li , Juan Li
- Applicant: Hunan University of Chinese Medicine
- Applicant Address: CN Hunan
- Assignee: Hunan University of Chinese Medicine
- Current Assignee: Hunan University of Chinese Medicine
- Current Assignee Address: CN Hunan
- Priority: CN201710173690.4 20170322
- International Application: PCT/CN2018/080074 WO 20180322
- International Announcement: WO2018/171684 WO 20180927
- Main IPC: C07D221/18
- IPC: C07D221/18 ; B01D15/08 ; B01D11/02 ; A61K31/00 ; B01D11/04
![7H-azulene [1,2,3-i,j] isoquinolin-7-one compound, single crystal and use thereof](/abs-image/US/2022/04/26/US11312687B2/abs.jpg.150x150.jpg)
Abstract:
A 7H-azulene [1,2,3-i,j] isoquinolin-7-one compound, a single crystal and a use thereof are provided. The compound has a structure as shown in a formula (I). The present invention obtains a crude extract of Acorus calamus L., then extracts with different polar solvents in sequence and separates column chromatography to obtain a novel alkaloid compound, which is expected to be developed into a novel class of drug exerting neuroprotective effects, so as to prevent and treat senile dementia, stroke and epilepsy diseases.
Public/Granted literature
- US20190194138A1 7H- azulene [1,2,3-i,j] isoquinolin-7-one compound, single crystal and use thereof Public/Granted day:2019-06-27
Information query
