Invention Grant
- Patent Title: Pyranopyrazole and pyrazolopyridine immunomodulators for treatment of autoimmune diseases
-
Application No.: US16767936Application Date: 2018-11-28
-
Publication No.: US11312723B2Publication Date: 2022-04-26
- Inventor: Manish P. Ponda , Harold Selnick , Melissa Egbertson , Jan L. Breslow
- Applicant: The Rockefeller University
- Applicant Address: US NY New York
- Assignee: The Rockefeller University
- Current Assignee: The Rockefeller University
- Current Assignee Address: US NY New York
- Agency: Heslin Rothenberg Farley & Mesiti, P.C.
- International Application: PCT/US2018/062702 WO 20181128
- International Announcement: WO2019/108565 WO 20190606
- Main IPC: C07D491/052
- IPC: C07D491/052 ; C07D471/04 ; C07D519/00
Abstract:
Pyranoyrazoles and pyrazolopyridines of formula I or formula II are disclosed: These compounds inhibit Coagulation Factor XIIa in the presence of thrombin and other coagulation factors. They are useful to treat autoimmune diseases.
Public/Granted literature
- US20200369677A1 PYRANOPYRAZOLE AND PYRAZOLOPYRIDINE IMMUNOMODULATORS FOR TREATMENT OF AUTOIMMUNE DISEASES Public/Granted day:2020-11-26
Information query
