Invention Grant
- Patent Title: Heterotandem bicyclic peptide complex
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Application No.: US16941588Application Date: 2020-07-29
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Publication No.: US11312749B2Publication Date: 2022-04-26
- Inventor: Gemma Mudd , Punit Upadhyaya , Kevin McDonnell , Johanna Lahdenranta
- Applicant: BicycleTx Limited
- Applicant Address: GB Cambridge
- Assignee: BicycleTx Limited
- Current Assignee: BicycleTx Limited
- Current Assignee Address: GB Cambridge
- Agency: Dechert LLP
- Agent Andrea L. C. Reid; Gang Wang
- Main IPC: C07K7/08
- IPC: C07K7/08 ; A61P35/00 ; A61K9/00 ; A61K38/12 ; A61K38/00
Abstract:
The present invention relates to a heterotandem bicyclic peptide complex which comprises a first peptide ligand, which binds to EphA2, conjugated via a linker to two second peptide ligands, which bind to CD137. The invention also relates to the use of said heterotandem bicyclic peptide complex in preventing, suppressing or treating cancer.
Public/Granted literature
- US20210069287A1 HETEROTANDEM BICYCLIC PEPTIDE COMPLEX Public/Granted day:2021-03-11
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