Invention Grant
- Patent Title: Assay for the detection of alpha-synuclein seeding activity associated with synucleinopathies
-
Application No.: US16652804Application Date: 2018-09-26
-
Publication No.: US11313867B2Publication Date: 2022-04-26
- Inventor: Byron Winslow Caughey , Bradley Richard Groveman , Christina Doriana Groveman , Lynne DePuma Raymond , Andrew Gregory Hughson
- Applicant: The U.S.A., as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US MD Bethesda
- Assignee: The U.S.A., as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The U.S.A., as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Bethesda
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2018/052968 WO 20180926
- International Announcement: WO2019/070480 WO 20190411
- Main IPC: G01N33/68
- IPC: G01N33/68 ; G01N33/543
Abstract:
Methods are disclosed for determining whether a subject has a synucleinopathy. Methods are also disclosed for detecting misfolded alpha synuclein (αSyn) in a biological sample or fraction thereof. These methods include the use of an αSyn seeding assay.
Public/Granted literature
- US20200232996A1 ASSAY FOR THE DETECTION OF ALPHA-SYNUCLEIN SEEDING ACTIVITY ASSOCIATED WITH SYNUCLEINOPATHIES Public/Granted day:2020-07-23
Information query
IPC分类:
