An embodiment includes duplicating an input dataset being input to a model predictive control (MPC) module for input to a first Hierarchical Temporal Memory (HTM) network. The embodiment also includes generating system behavior data using the MPC module for characteristic data of the input dataset. The embodiment also includes generating first HTM prediction data from the input dataset and the system behavior data using the first HTM network, the first HTM prediction data comprising predictions for respective dimensions of the system. The embodiment also includes generating second HTM prediction data from the first HTM prediction data and system output data using a second HTM network, the second HTM prediction data comprising a distinction between the first HTM prediction and the system output data. Finally, the embodiment includes determining that the distinction of the second HTM prediction data indicates an anomaly and adjusting system input data based on the anomaly.