A processor may receive information about one or more environmental factors. The processor may predict, based on the one or more environmental factors, that a particular datacenter in a distributed computing environment will experience elevated bit-flip error rates during a certain time period. The processor may select, based on the predicted elevated bit-flip error rates, one or more specific applications in the particular datacenter to be protected. The processor may protect the selected one or more specific applications during the certain time period of the predicted elevated bit-flip rates.