A system for monitoring a tank truck operation platform and for guiding and positioning vehicles and a method of using the same, the system includes operation platforms. Each of the operation platforms is provided with a lifting support. The operation platform is installed with an upper-position sensor, a lower-position sensor, and a stress sensor, which communicate with a central control device mounted on the operation platform. The central control device communicates with a distance meter and an in-place sensor for detecting the vehicle. The central control device may send signals to a display device, and information of platform status and vehicle position guidance are displayed on the display device to offer the driver with guidance information including whether the platform is safe and available, the moving direction of the vehicle, and position relative to the platform. Meanwhile, the central control device can receive identification information sent by the vehicle.