Invention Grant
- Patent Title: Use of carotenoid derivatives to reduce the toxicity and increase the efficacy of anti-EGFR antitumor treatments
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Application No.: US16478915Application Date: 2018-01-15
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Publication No.: US11318108B2Publication Date: 2022-05-03
- Inventor: Mauro Moroni , Paolo Pedrazzoli , Marco Giulio Giuseppe Pirovano
- Applicant: ASSOCIAZIONE ONCOLOGICA MILANESE AMO LA VITA ONLUS
- Applicant Address: IT Milan
- Assignee: ASSOCIAZIONE ONCOLOGICA MILANESE AMO LA VITA ONLUS
- Current Assignee: ASSOCIAZIONE ONCOLOGICA MILANESE AMO LA VITA ONLUS
- Current Assignee Address: IT Milan
- Priority: IT102017000005649 20170119
- International Application: PCT/IB2018/050229 WO 20180115
- International Announcement: WO2018/134717 WO 20180726
- Main IPC: A61K31/01
- IPC: A61K31/01 ; A61K39/395 ; A61K45/06 ; C09K15/00 ; A61P39/00 ; A61P35/00 ; A61K47/42 ; C07K16/28 ; C07K16/24
Abstract:
The present invention refers to compounds of the carotenoid class, such as lycopene or lacto-lycopene, for their use in the treatment and/or prevention of toxicity caused by antitumor drugs, as well as their use in the treatment or remission of tumors in combination with antitumor drugs. Finally, the present invention refers to the combination of the above set forth compounds and drugs with antitumor action.
Public/Granted literature
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