Invention Grant
- Patent Title: Methods and compositions related to STK1-targeted small molecules as antibiotic resistance breakers
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Application No.: US16627575Application Date: 2018-07-02
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Publication No.: US11318141B2Publication Date: 2022-05-03
- Inventor: Vijay Pancholi
- Applicant: Ohio State Innovation Foundation
- Applicant Address: US OH Columbus
- Assignee: Ohio State Innovation Foundation
- Current Assignee: Ohio State Innovation Foundation
- Current Assignee Address: US OH Columbus
- Agency: Meunier Carlin & Curfman LLC
- International Application: PCT/US2018/040602 WO 20180702
- International Announcement: WO2019/006459 WO 20190103
- Main IPC: A61K31/545
- IPC: A61K31/545 ; A61P31/04 ; A61K31/519
Abstract:
Disclosed are methods and compositions related to STK1 inhibitors, such as Inh2-B1 (methyl 5-oxo-3-(phenyl carbamoyl)-1-thioxo-4,5dihydro[1,3]thiazolo[3,4-a]quinazoline-8-carboxylate). The STK1 inhibitors can act as an antibiotic resistance breakers against multidrug-resistant Staphylococcus aureus.
Public/Granted literature
- US20200222416A1 METHODS AND COMPOSITIONS RELATED TO STK1-TARGETED SMALL MOLECULES AS ANTIBIOTIC RESISTANCE BREAKERS Public/Granted day:2020-07-16
Information query
IPC分类:
