Invention Grant
- Patent Title: Isolation of fusion-competent myoblasts and therapeutic applications thereof related to muscular dystrophy
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Application No.: US15781709Application Date: 2016-12-09
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Publication No.: US11318167B2Publication Date: 2022-05-03
- Inventor: Gabsang Lee , InYoung Choi , HoTae Lim , Kathryn R. Wagner
- Applicant: THE JOHNS HOPKINS UNIVERSITY
- Applicant Address: US MD Baltimore
- Assignee: THE JOHNS HOPKINS UNIVERSITY
- Current Assignee: THE JOHNS HOPKINS UNIVERSITY
- Current Assignee Address: US MD Baltimore
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Peter F. Corless
- International Application: PCT/US2016/065704 WO 20161209
- International Announcement: WO2017/100498 WO 20170615
- Main IPC: A61K35/34
- IPC: A61K35/34 ; C12N5/00 ; A61P21/00 ; A61K35/545 ; C12N5/077 ; G01N33/50
Abstract:
Described are methods of isolating high purity myoblasts that are used to create novel DMD model systems and methods using human induced pluripotent stem cells (hiPSCs). Also described are therapeutic methods based on the use of these myoblasts.
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