Invention Grant
- Patent Title: Use of genetically engineered bacterium of attenuated Salmonella typhimurium in for treating liver cancer
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Application No.: US17067636Application Date: 2020-10-09
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Publication No.: US11318172B2Publication Date: 2022-05-03
- Inventor: Allan Zijian Zhao , Sujin Zhou , Yan Lin , Zhenggang Zhao , Fanghong Li
- Applicant: GUANGZHOU SINOGEN PHARMACEUTICAL CO., LTD
- Applicant Address: CN Guangzhou
- Assignee: GUANGZHOU SINOGEN PHARMACEUTICAL CO., LTD
- Current Assignee: GUANGZHOU SINOGEN PHARMACEUTICAL CO., LTD
- Current Assignee Address: CN Guangzhou
- Agency: Jun He Law Offices P.C.
- Agent James J. Zhu
- Priority: CN201510546063.1 20150831
- Main IPC: A61K35/74
- IPC: A61K35/74 ; A61P35/00 ; C12N15/63 ; A61K9/00
Abstract:
Provided is use of a genetically engineered bacterium of attenuated Salmonella typhimurium for treating liver cancer. The bacterium is attenuated Salmonella typhimurium VNP20009 carrying a plasmid cloned with a methioninase gene. Also provided is a construction method of the bacterium.
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