Invention Grant
- Patent Title: Attenuated mutant dengue viruses comprising a mutation in the NS5 non-structural protein
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Application No.: US16684103Application Date: 2019-11-14
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Publication No.: US11318196B2Publication Date: 2022-05-03
- Inventor: Stephen S. Whitehead , Brian R. Murphy , Kathryn A. Hanley , Joseph E. Blaney , Ching-Juh Lai
- Applicant: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
- Applicant Address: US MD Rockville
- Assignee: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
- Current Assignee Address: US MD Rockville
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C12N7/00 ; C12N7/04 ; A61K39/00 ; A61K39/295 ; C12Q1/70
Abstract:
A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.
Public/Granted literature
- US20200085939A1 DEVELOPMENT OF MUTATIONS USEFUL FOR ATTENUATING DENGUE VIRUSES AND CHIMERIC DENGUE VIRUSES Public/Granted day:2020-03-19
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