An application unit comprises an application mechanism with an impression cylinder, a forme cylinder, and a supply roller, along with a positioning device and a magazine for supply rollers, which magazine is located below the application mechanism. The magazine has magazine receptacles for supply rollers and a movable repositioning device, by the use of which, the magazine receptacles can be placed in different magazine positions. One of the magazine positions is a change position, and when a magazine receptacle is located in that change position, a supply roller can be transferred, with respect to a positioning direction, between the magazine receptacle and a remote region of a roller positioning path that connects the magazine to the application mechanism. The positioning direction deviates no more than 45 degrees from a vertical direction. One of the magazine positions is a loading position, and when a magazine receptacle is located in the loading position, a supply roller can be transferred along a loading path with respect to a loading direction, between the magazine receptacle and a loading area. The loading direction deviates no more than 30 degrees from at least one horizontal direction.