Invention Grant
- Patent Title: Alpha alkylation of aldehyde with a polycyclic olefin
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Application No.: US16605309Application Date: 2018-04-17
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Publication No.: US11319272B2Publication Date: 2022-05-03
- Inventor: Julie Quintaine , David W. C. MacMillan
- Applicant: FIRMENICH SA
- Applicant Address: CH Geneva
- Assignee: FIRMENICH SA
- Current Assignee: FIRMENICH SA
- Current Assignee Address: CH Geneva
- Agency: Armstrong Teasdale LLP
- Priority: EP17169442 20170504
- International Application: PCT/EP2018/059780 WO 20180417
- International Announcement: WO2018/192923 WO 20181025
- Main IPC: C07C45/68
- IPC: C07C45/68 ; C11B9/00 ; C07C47/225 ; A61K8/33 ; A61Q5/02 ; A61Q13/00 ; A61Q19/10 ; B01J31/22 ; C07C45/69 ; C07C47/115 ; C11D3/00 ; C11D3/50

Abstract:
The alpha alkylation of an aldehyde with a polycyclic olefin followed by a ring opening step is presented in order to provide a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof and where in R represents a hydrogen atom or C1-8 linear alkyl group; R1, R2, R3, and R4 represent, when taken separately, independently of each other, a hydrogen atom or a C1-2 linear alkyl group or a C3-4 linear or branched alkyl group; or R2 and R3, when taken together, represent a C4-10 linear, branched or cyclic alkanediyl group and n is 1 or 2 is presented.
Public/Granted literature
- US20210147328A1 ALPHA ALKYLATION OF ALDEHYDE WITH A POLYCYCLIC OLEFIN Public/Granted day:2021-05-20
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