Invention Grant
- Patent Title: Polymorps of cariprazine hydrochloride and preparation method thereof and use of same
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Application No.: US16840518Application Date: 2020-04-06
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Publication No.: US11319293B2Publication Date: 2022-05-03
- Inventor: Xiaoming Meng
- Applicant: SHANGHAI BEGREAT PHARMATECH
- Applicant Address: CN Shanghai
- Assignee: SHANGHAI BEGREAT PHARMATECH
- Current Assignee: SHANGHAI BEGREAT PHARMATECH
- Current Assignee Address: CN Shanghai
- Agency: Metis IP LLC
- Priority: WOPCT/CN2018/106868 20180921
- Main IPC: C07D241/04
- IPC: C07D241/04
Abstract:
The present disclosure discloses crystal forms A, B, and C of trans-N-{4-[2-[4-(2,3-dichlorophenyl)-piperazine-1-yl]-ethyl]-cyclohexyl}-N′,N′-dimethylurea hydrochloride, a preparation method, and a medicinal use thereof. Compared to the existing crystalline forms, the new crystalline forms have clear advantages with respect to solubility, stability, and the preparation process.
Public/Granted literature
- US20200231552A1 NOVEL POLYMORPS OF CARIPRAZINE HYDROCHLORIDE AND PREPARATION METHOD THEREOF AND USE OF SAME Public/Granted day:2020-07-23
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