Invention Grant
- Patent Title: Substituted phenyloxetane and phenyltetrahydrofuran compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
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Application No.: US16753043Application Date: 2018-10-04
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Publication No.: US11319295B2Publication Date: 2022-05-03
- Inventor: Catherine M. White , Meredeth Ann McGowan , Yongxin Han , Nunzio Sciammetta
- Applicant: MERCK SHARP & DOHME CORP. , Catherine M. White , Meredeth Ann McGowan , Yongxin Han , Nunzio Sciammetta
- Applicant Address: US NJ Rahway; US MA Newton Center; US MA Boston; US MA Needham; US MA Sudbury
- Assignee: MERCK SHARP & DOHME CORP.,Catherine M. White,Meredeth Ann McGowan,Yongxin Han,Nunzio Sciammetta
- Current Assignee: MERCK SHARP & DOHME CORP.,Catherine M. White,Meredeth Ann McGowan,Yongxin Han,Nunzio Sciammetta
- Current Assignee Address: US NJ Rahway; US MA Newton Center; US MA Boston; US MA Needham; US MA Sudbury
- Agent Yong Zhao; Catherine D. Fitch
- International Application: PCT/US2018/054274 WO 20181004
- International Announcement: WO2019/074748 WO 20190418
- Main IPC: C07D305/08
- IPC: C07D305/08 ; A61P37/00 ; A61P25/28 ; A61P31/12 ; A61P25/24 ; A61P27/12 ; A61P35/00 ; C07D307/22 ; C07D307/24 ; C07D405/04 ; A61K45/06
Abstract:
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (Formula (I)). Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.
Public/Granted literature
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