Invention Grant
- Patent Title: Substituted carboxamides as inhibitors of WDR5 protein-protein binding
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Application No.: US16080866Application Date: 2017-03-01
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Publication No.: US11319299B2Publication Date: 2022-05-03
- Inventor: Rima Al-Awar , Carlos Armando Zepeda-Velazquez , Gennady Poda , Methvin Isaac , David Uehling , Brian Wilson , Babu Joseph , Yong Liu , Pandiaraju Subramanian , Ahmed Mamai , Michael Prakesch , Julia Kathleen Stille
- Applicant: PROPELLON THERAPEUTICS INC.
- Applicant Address: CA Toronto
- Assignee: PROPELLON THERAPEUTICS INC.
- Current Assignee: PROPELLON THERAPEUTICS INC.
- Current Assignee Address: CA Toronto
- Agency: Cooley LLP
- Agent J. Dean Farmer; Serge R. Banini
- International Application: PCT/CA2017/050269 WO 20170301
- International Announcement: WO2017/147700 WO 20170908
- Main IPC: A61K31/167
- IPC: A61K31/167 ; C07C233/15 ; C07D401/12 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D403/10 ; C07D401/10 ; C07D417/12 ; C07D417/14 ; A61K45/06 ; A61P35/02
Abstract:
The present application is directed to compounds of Formula I: compounds comprising these compounds and their uses, for example as medicaments for the treatment of diseases, disorders or conditions mediated or treatable by inhibition of binding between WDR5 protein and its binding partners.
Public/Granted literature
- US20190112290A1 INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING Public/Granted day:2019-04-18
Information query
