Invention Grant
- Patent Title: PRC1 inhibitors and methods of treatment therewith
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Application No.: US16434508Application Date: 2019-06-07
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Publication No.: US11319302B2Publication Date: 2022-05-03
- Inventor: Tomasz Cierpicki , Jolanta Grembecka , Weijiang Ying , Yiwu Yao , Felicia Gray , Qingjie Zhao
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones SC
- Agent David W. Staple
- Main IPC: C07D403/14
- IPC: C07D403/14 ; C07D403/04 ; C07D405/14 ; C07D413/14 ; C07D417/14 ; C07D471/04 ; C07D471/16 ; C07D493/10 ; C07D498/06 ; C07D498/16 ; C07D513/16 ; A61K9/00 ; A61K45/06
Abstract:
Provided herein are small molecule inhibitors of Polycomb Repressive Complex 1 (PRC1) activity, and methods of use thereof for the treatment of disease, including leukemia and other cancers, as well as other diseases dependent on the activity of PRC1.
Public/Granted literature
- US20200039963A1 PRC1 INHIBITORS AND METHODS OF TREATMENT THEREWITH Public/Granted day:2020-02-06
Information query
