Invention Grant
- Patent Title: Antibody facilitating programmed necrosis of cells and application thereof
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Application No.: US15745624Application Date: 2016-07-18
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Publication No.: US11319366B2Publication Date: 2022-05-03
- Inventor: Shisong Jiang , Wenshu Lu
- Applicant: SHANGHAI JW INFLINHIX CO., LTD.
- Applicant Address: CN Shanghai
- Assignee: SHANGHAI JW INFLINHIX CO., LTD.
- Current Assignee: SHANGHAI JW INFLINHIX CO., LTD.
- Current Assignee Address: CN Shanghai
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: CN201510424724.3 20150717
- International Application: PCT/CN2016/090322 WO 20160718
- International Announcement: WO2017/012525 WO 20170126
- Main IPC: C07K16/24
- IPC: C07K16/24 ; C12N15/63 ; C12N5/10 ; A61K39/395 ; G01N33/577 ; G01N33/564 ; G01N33/68

Abstract:
The present invention provides an antibody facilitating programmed necrosis of cells. The antibody can cause programmed necrosis of cells in the presence of tumor necrosis factor (TNF). Therefore, an inhibitor for the antibody can be used in the treatment of inflammatory diseases. Further, the present invention provides the application of the antibody facilitating programmed necrosis of cells in the inflammatory disease prognosis.
Public/Granted literature
- US20190062417A1 ANTIBODY FACILITATING PROGRAMMED NECROSIS OF CELLS AND APPLICATION THEREOF Public/Granted day:2019-02-28
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