Invention Grant
- Patent Title: Method for producing hypromellose phthalate
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Application No.: US16521237Application Date: 2019-07-24
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Publication No.: US11319384B2Publication Date: 2022-05-03
- Inventor: Akiko Tsuchida , Taishi Kitaguchi , Akira Kitamura , Mitsuo Narita
- Applicant: SHIN-ETSU CHEMICAL CO., LTD.
- Applicant Address: JP Tokyo
- Assignee: SHIN-ETSU CHEMICAL CO., LTD.
- Current Assignee: SHIN-ETSU CHEMICAL CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Myers Bigel, P.A.
- Priority: JPJP2018-139248 20180725
- Main IPC: C08B3/10
- IPC: C08B3/10

Abstract:
There is provided a method for producing hypromellose phthalate (HPMCP), the method not requiring any special device, and facilitating removal of impurities. More specifically, there is provided a method for producing HPMCP, including an esterification step of esterifying hypromellose with a carboxybenzoylating agent in the presence of an aliphatic carboxylic acid to obtain a reaction product solution containing HPMCP; a precipitation step of precipitating the HPMCP by mixing the reaction product solution with water to obtain a suspension of the precipitated HPMCP; a neutralization step of neutralizing the suspension with a basic substance to obtain a neutralized suspension; and a washing step of washing the HPMCP contained in the neutralized suspension to obtain the washed HPMCP.
Public/Granted literature
- US20200031953A1 METHOD FOR PRODUCING HYPROMELLOSE PHTHALATE Public/Granted day:2020-01-30
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