Invention Grant
- Patent Title: Hydrophilic polymer derivative having self-immolative acetal linker and conjugate using same
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Application No.: US16493033Application Date: 2018-03-22
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Publication No.: US11319408B2Publication Date: 2022-05-03
- Inventor: Takuma Tsubusaki , Shinya Tamagawa
- Applicant: NOF CORPORATION
- Applicant Address: JP Tokyo
- Assignee: NOF CORPORATION
- Current Assignee: NOF CORPORATION
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JPJP2017-067636 20170330
- International Application: PCT/JP2018/011485 WO 20180322
- International Announcement: WO2018/180914 WO 20181004
- Main IPC: C08G65/331
- IPC: C08G65/331
Abstract:
To provide a hydrophilic polymer derivative having a novel linker technique which is able to from a hydrophilic polymer pro-drug of a drug containing an amino group or the like in order to overcome the restrictions of conventional hydrophilic polymer pro-drugs. A hydrophilic polymer derivative containing a hydrophilic polymer moiety and an acetal moiety, wherein the hydrophilic polymer derivative contains a structure represented by formula (1) or formula (2):
Public/Granted literature
- US20200010620A1 HYDROPHILIC POLYMER DERIVATIVE HAVING SELF-IMMOLATIVE ACETAL LINKER AND CONJUGATE USING SAME Public/Granted day:2020-01-09
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