Invention Grant
- Patent Title: Nucleic acids for inhibiting expression of LPA in a cell
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Application No.: US16763458Application Date: 2018-11-13
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Publication No.: US11319537B2Publication Date: 2022-05-03
- Inventor: Sibylle Dames , Steffen Schubert , Stephan Tenbaum , Christian Frauendorf , Lucas Bethge , Judith Hauptmann , Adrien Weingärtner , David Anthony Rider
- Applicant: SILENCE THERAPEUTICS GMBH
- Applicant Address: DE Berlin
- Assignee: SILENCE THERAPEUTICS GMBH
- Current Assignee: SILENCE THERAPEUTICS GMBH
- Current Assignee Address: DE Berlin
- Agency: Marshall, Gerstein & Borun LLP
- Priority: EP17201449 20171113,EP18179175 20180621,GB1815915 20180928
- International Application: PCT/EP2018/081106 WO 20181113
- International Announcement: WO2019/092283 WO 20190516
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/113
Abstract:
The present invention relates to products and compositions and their uses. In particular the invention relates to nucleic acid products that interfere with the LPA gene expression or inhibit its expression for use as treatment, prevention or reduction of risk of suffering cardiovascular disease such as coronary heart disease or aortic stenosis or stroke or any other disorder, pathology or syndrome linked to elevated of Lp(a)-containing particles.
Public/Granted literature
- US20210123048A1 NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF LPA IN A CELL Public/Granted day:2021-04-29
Information query
