A quick connection device with a double-checked locking mechanism includes a connection housing and a locking mechanism, the locking mechanism including a first locking mechanism inserted into the connection housing and having a pedestal from which a pair of retaining arms extends, the pair of retaining arms being connected by a connection strip to form a retaining ring for fitting with an opposite plug-in tube, and having an elastic reset component; and a second locking mechanism inserted into the connection housing having a base from which locking arms and holding arms extend, the first locking mechanism being inserted between the locking arms and the holding arms, wherein the locking arms support a portion of the first locking mechanism and the second locking mechanism prevents movement of the first locking mechanism from the locked position to an unlocked position when the second locking mechanism is in a locked position.